Folate requirement in pregnancy.

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Folate requirement in pregnancy.

economic strata and are often residents of rural areas. Diet lacks high-class proteins and consists mostly of cereals and a small quantity of pulses. Very low levels of total serum proteins and albumin are noted in hospitalized patients. The presumptive evidence of protein malnutrition and deprivation is strong, unlike the cryptogenic types in Britain. Less than a quarter of patients give a his...

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Homocysteine and folate in pregnancy.

The importance of folate during pregnancy was addressed 40 years ago by Bryan Hibbard (1 ) in his study of folate status in 1484 low-income obstetric patients from Liverpool. He assessed folate status as urinary excretion of formiminoglutamic acid. Abnormal formiminoglutamic acid excretion was related not only to placental abruption and spontaneous abortion but also to adverse outcomes in previ...

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Folate and homocysteine levels in pregnancy.

This study aims to determine serum folate and plasma homocysteine levels in healthy pregnant women following a live birth and compare them with healthy non-pregnant women. Fifty healthy gravid multiparous women are included in the study and 25 normal non-pregnant female subjects act as controls (group I). The pregnant women are divided into two groups according to interpregnancy interval: group...

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Folic acid and folate binding protein in pregnancy.

Folic acid and folate binding protein (FABP) concentrations were determined in 208 pregnant women as well as in 50 non-pregnant women. Serum folate levels in pregnant women were significantly lower than those of the non-pregnant group. Anaemic pregnant women also had lower serum folate concentrations than those of the non-anaemic pregnant women. Ninetyeight of 208 (47.1%) pregnant women had ser...

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Taking folate in pregnancy and risk of maternal breast cancer.

Taking folate before conception and then for the first three months of pregnancy reduces the risk of recurrence of neural tube defects, and fortification of food has been proposed. The effects of long term exposure to high concentrations of supplemental folate are unknown, and antimetabolite effects are theoretically possible. Data on the long term effects of increased folate intake in pregnanc...

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ژورنال

عنوان ژورنال: BMJ

سال: 1968

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.5604.562